Mutating Corona Virus

[tobyjugg2]

39 minutes ago, unclebulgaria67 said:

China is taking risk of Covid much more seriously than other countries. Do they know something that scientists and others around the world don't know ?

 

If Chinese scientists have been studying Covid for years, are they aware of possible health impacts that people may have following infection ?

 

No. Its quite well known and have linked many references here for some considerable time. Not read them?

 

No. Long covid aka post-COVID-19 syndrome, post-COVID-19 condition, post-acute sequelae of COVID-19, or chronic COVID syndrome health issues are well known here, although you might not think so if you just listen to the alls well garbage from Johnsons cabal. reports go back a year+

 

If you have long Covid, as I did, don’t give up hope. Recovery is possible | Paul Garner | The Guardian

WWW.THEGUARDIAN.COM

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It’s different for everyone. In my case, finding an explanation for my symptoms that made sense was the key, says professor of infectious...

 

 

NHS England » Enhanced service specification: Long COVID 2021/22

WWW.ENGLAND.NHS.UK

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Health and high quality care for all, now and for future generations

 

 

Long-term effects of coronavirus (long COVID) - NHS

WWW.NHS.UK

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NHS information about the long-term effects some people can have after having coronavirus (COVID-19). These are sometimes called "long COVID".

 

Coronavirus » Post-COVID Syndrome (Long COVID)

WWW.ENGLAND.NHS.UK

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Health and high quality care for all, now and for future generations

 

Long Covid: Symptoms include fatigue, weakness and dyspnoea | Express.co.uk

WWW.EXPRESS.CO.UK

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COVID is a cruel lottery: for some, it results in a mild illness that clears up in a few days. Others are bedevilled for months after the initial infection has...

 

 

Long COVID - Wikipedia

EN.WIKIPEDIA.ORG

 

 

Long COVID affects 1 in 5 people following infection. Vaccination, masks and better indoor air are our best protections

THECONVERSATION.COM

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Studies show long COVID is common enough to be a major public-health threat. It can damage the brain and other organs and may remain silent...

 

 

Living with long COVID

WWW.BUPA.CO.UK

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Dr Luke James explains what long COVID is, including what we know about it so far and some ways to help you manage if it affects you.

 

 

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Long COVID: What is it and how can it be treated? | Nuffield Health

WWW.NUFFIELDHEALTH.COM

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Find out the symptoms of long COVID and how you can self-manage and get rehabilitation for these

 

 

 

Maybe they are concerned about mutations rates in dense populations as we saw in London and New York and other population centers ... repeatedly

Edited April 18, 2022 by tobyjugg2

[tobyjugg2]

or if thats too much info and somewhat overwhelming ...

 

Heres just 1 last updated feb 2021 with details from March 2020 highlighting long covid was coming

 

Long COVID – we’ve been here before

WWW.BMA.ORG.UK

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Long COVID is a new condition, but those who have endured years of ME/CFS can share their common experience – and a long history of being...

 

[unclebulgaria67]

I read an article recently about an NHS worker who paid £300 for a specialised heart scan, because standard checks did not reveal anything.  They had been suffering from a number of symptoms reported for long Covid. 

 

The addition heart scan revealed reduced heart function.

 

There have been studies into this, so there is some evidence for this.  BMJ link below.

 

Covid-19: Even mild infections can cause long term heart problems, large study finds

WWW.BMJ.COM

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Infection with SARS-CoV-2 can cause cardiovascular problems for up to a year, not just during the acute phase, a large study has found.1 The authors...

 

 

[tobyjugg2]

I have seen studies (linked here) that vaccination reduces both the chance of getting and the severity and duration if you get it - of 'long covid.

 

What greatly concerns me is that we are just getting hints of vaccines targeting the delta version, when we are already at 3rd generation Omicron.

We should be at a stage where cocktails of vaccines (like for flu) are available and quickly updated. Yes i know that flu strains are 'more static/stable' than COVID, but the world of infections is moving on - and so must we to simply keep up.

 

Still expecting a real sh**storm of a recombination/mutation that mixes with something else really nasty and the resultant being something like truly airborn ebola/covid mix that will spread like wildfire among dense human populations and transport systems.

 

I really do at least half believe some of the conspiracy theories that certain 'elite' want that as a population reduction scheme while they are locked away safe - and the simple fact that should Johnson get it - he wont be waiting 8 hours for an ambulance and then lying in it for another 8 hours before he spends a few days on a stretcher in a corridor ....

... he'll be VIP'd straight into a private room with 2 nurses all to himself ... again.

 

 

Edited April 18, 2022 by tobyjugg2

[tobyjugg2]

On 15/04/2022 at 20:26, tobyjugg2 said:

Theres lots of reports of apparent mysterious increased cases of hepatitis and liver failure in young children

 

Distressing and disturbing as this is, :

 

"There is no link to the COVID-19 vaccine. None of the currently confirmed cases in the UK has been vaccinated."

 

adenovirus infections is one possible component, as is covid infection

 

 

More hepatitis cases in young children likely to emerge in coming days, says WHO

WWW.INDEPENDENT.CO.UK

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UK doctors and scientists investigating 74 cases of inflammatory liver condition

 

 

Increase in hepatitis (liver inflammation) cases in children under investigation - GOV.UK

WWW.GOV.UK

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The UK Health Security Agency (UKHSA) has recently detected higher than usual rates of liver inflammation (hepatitis) in children. Similar cases are...

 

 

 

 

Doctors reveal probable cause of mysterious child hepatitis

WWW.INDEPENDENT.CO.UK

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Investigations ‘increasingly’ point to F41 strain of adenovirus after string of sudden cases around world

 

[tobyjugg2]

Unlawfully proroguing parliament

Unlawfully giving VIP pals contracts

 

Now

 

Covid: discharging untested patients into care homes was unlawful, says court | Coronavirus | The Guardian

WWW.THEGUARDIAN.COM

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High court judgment deals blow to claim government threw ‘protective ring’ around vulnerable residents

 

[honeybee13]

Well done the High Court. I suppose the government will waste further public money or try to dissuade the people bringing the case from continuing by threatening sky high costs like they have in the past.

[tobyjugg2]

Loads of unlawful - 

but NOTHING in the way of convictions

 

In fact it seems the Met is doing its absolute best, including breaching its on rules of conducting investigations, to protect these populists.

[honeybee13]

Commentator David Allen Green has posted his thoughts on non-tested patients being discharged into care homes. I think it's fair to say he isn't impressed.

 

The false and misleading statements of Boris Johnson and Matt Hancock about the Covid care homes judgment – The Law and Policy Blog

DAVIDALLENGREEN.COM

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29 April 2022 On Wednesday the prime minister was asked by Daisy Cooper MP about the high court decision holding that the government had acted...

 

And another one.

 

How one paragraph in the significant Covid and care homes judgment describes Matt Hancock’s lethal, unlawful policy – The Law and Policy Blog

DAVIDALLENGREEN.COM

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28th April 2022 One of the most outstanding lawyers I know works a lot with care home clients. Sometime ago they told me about what happened when...

 

[tobyjugg2]

How often can you be infected with the Omicron variant of the coronavirus? Scientists have an unsettling answer: repeatedly, sometimes within months.

- NYT

[tobyjugg2]

Worth a peruse

 

I've flagged this as needing far more examination:

Many older (and not so old)  people are on anti-inflammatory medication  although they commonly have other health issues

 

 

FcγR-mediated SARS-CoV-2 infection of monocytes activates inflammation

WWW.NATURE.COM

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Antibody-mediated SARS-CoV-2 uptake by monocytes and macrophages triggers inflammatory cell death that aborts the production of infectious...

 

[BazzaS]

10 hours ago, tobyjugg2 said:

Worth a peruse

 

I've flagged this as needing far more examination:

Many older (and not so old)  people are on anti-inflammatory medication  although they commonly have other health issues

 

I’m sure Nature is grateful for you flagging it as needing more examination !

 

Until then, what is your point about older people and anti-inflammatory medicines?

or are you just quoting learned articles at random in the hope that occasionally you’ll either “get lucky” with a comment, or that you’ll gull someone into thinking you actually understand the cytokine / interleukin / inflammasome pathways…..

The utility of steroids (dexamethasone) for in-patients needing oxygen has been demonstrated by the RECOVERY trial.

I can’t see where this has been analysed on a sub-group basis for older people on anti-inflammatory meds : are you suggesting the trial has “missed a trick”?

 

What is your feeling on which interleukin needs to be targeted? And should it be upregulated or downregulated?

 

More to the point (since I don’t expect an answer that shows any degree of understanding, if you answer at all) :

 

What is your point, rather than just posting journal articles at random!

Edited May 20, 2022 by BazzaS

[tobyjugg2]

Flu vaccine could cut COVID risk

Influenza vaccines might prevent COVID-19, particularly in its most severe forms. A preprint study of more than 30,000 health-care workers in Qatar found that those who got a flu shot were nearly 90% less likely to develop severe COVID-19 over the next few months, compared with those who hadn’t been recently vaccinated against flu. It’s unclear why flu vaccines — which are composed of killed influenza viruses — would also protect against COVID-19 or how long this protection lasts.

Nature | 4 min read
Reference: medRxiv preprint (not peer reviewed)

[honeybee13]

That sounds worth keeping an eye on, TJ. Thank you for posting the article.

[tobyjugg2]

perhaps somewhat more controversial for some

Far-UVC disinfection works in real rooms Real-world tests confirm that short-wavelength ultraviolet light, known as far-UVC, can disinfect air without harming people. Researchers found that far-UVC lamps effectively wiped out airborne Staphylococcus aureus bacteria in a room-sized chamber. Even when the bacteria were continuously released into the room, the lamps — combined with typical ventilation of around three air changes per hour — reduced the amount in the room by 92%, equivalent to 35 air changes per hour. Far-UVC light has long shown promise against airborne pathogens — including SARS-CoV-2 — in the laboratory. And, unlike other forms of UV light, it doesn’t damage human skin or eyes, or cause cancer. Physics World | 5 min read Reference: Scientific Reports paper       I personally wouldnt use this in homes - people really don't need sterile environments - bodies need to fight infections. But hopitals and care homes ... maybe ..

Edited May 26, 2022 by tobyjugg2

[BazzaS]

Sigh. Another “ohh, I’ll post something sexy, that I don’t really understand”.

 

it works in theory.

it works in practice, in limited and specific circumstances.

 

it FAILS in practice if you don’t know what you are doing. Shadows. Exposure from the contaminated items while setting up the decontamination run.

 

So, the item(s) must be physically clean.

Dirt? Creates a shadow, that the organism can be protected from the UVC.

 

Irregular shape of item to be disinfected?

risk of shadows, shadows -> organism can be protected from the UVC.

 

When SARS-CoV first ‘hit’, there were sites using UVC to decontaminate FFP3 masks for re-use (as the masks were in such short supply). The set up was designed by engineers with input from Infection Prevention teams, so that the limitations were mitigated, and a rig that “worked” was created.

 

The team involved published a paper on this.

 

I was asked by a friend (who was / is “extremely clinically vulnerable”) about UVC, for him to treat the shopping he was having delivered that couldn’t be left to stand for 48 hours. I sent him the link to the paper.

Then again, he is also a scientist and has an engineering focus too, while he could source / build a UVC rig, and would understand the uses, risks, benefits and limitations of its use, including correct use of PPE while handling the items for decontamination.

 

I wouldn’t try it for myself : how sure am I that the UV is safe? (Even if it is focused on UVC, am I sure there is no UV-B or UV-A)

For “Joe Q. Public” : how sure are you they’d get around the cleaning / shadows? (Or risk being exposed while cleaning?)

it might give them a false sense of security ……

 

care homes? No way

Edited May 26, 2022 by BazzaS

[tobyjugg2]

Regarding inflammation, background info and some relatively breaking news for anyone interested

 

What Is Inflammation?

WWW.VERYWELLHEALTH.COM

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Inflammation is the body’s natural response to dangers like illnesses and injuries. Chronic inflammation can lead to long-term health problems.

 

 

The inflammatory response

WWW.VIROLOGY.WS

 

 

The end of inflammation? New approach could treat dozens of diseases. | National Geographic

WWW.NATIONALGEOGRAPHIC.CO.UK

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Cancer, ageing, and severe COVID-19 have all been linked to damage from inflammation. Now scientists are flipping their focus to find new drugs...

 

[tobyjugg2]

COVID lessons from Japan

The number of COVID-19 cases and deaths per capita in Japan has been significantly lower than in peer countries. Japan has several distinctive characteristics: it has the world’s oldest population, its land is densely populated and its constitution prohibits strict lockdowns. While other countries focused on disinfection, Japan emphasized avoiding sanmitsu, the ‘3Cs’: closed environments, crowded conditions and close-contact settings. Virologist Hitoshi Oshitani, who advises the Japanese government on its pandemic response, looks back on what worked and considers what the future might hold.

 

Nature | 5 min read

 

d41586-022-01385-9.pdfd41586-022-01385-9.pdf

Edited May 30, 2022 by tobyjugg2

[honeybee13]

I don't have time to read that straight away, does it mention mask-wearing at all?

[tobyjugg2]

"masks are common across asia"

"Strong social pressure probably helped to boost protective measures, such as mask wearing, and minimized risky behaviours"

[tobyjugg2]

Which airlines have been most affected?

Airlines including British Airways and easyJet announced a string of flight cancellations shortly before Easter, as rising coronavirus cases led to high levels of staff absences.

Tui also made several last-minute cancellations over the weekend from airports including Gatwick, Birmingham and Bristol, as a result of “operational and supply chain issues”.

 

What is causing travel chaos at some UK airports and what are your rights? | Travel & leisure | The Guardian

WWW.THEGUARDIAN.COM

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With some airlines struggling to cope with the half-term holidays, what should you do if your plans are disrupted?

 

Edited May 31, 2022 by tobyjugg2

[honeybee13]

That's useful, TJ, thank you. You could also post it in our Holidays and airlines forum where people who are affected might see it.

[tobyjugg2]

Real issues are even more than that

Apparently although flight staff were furloughed, baggage handlers weren't .. apparently few want the jobs as reports are that the UK cost of living crisis means many expect collapse of holiday orders again

 

Reports of people queuing hours for flights then they are cancelled, or if they aren't the baggage doesn't get onto the plane with them ..

 

Horrendous.

 

 

[tobyjugg2]

"R" number for covid infections is now over 1, mainly due to the K4 asnd K5 omicron variants. Hospitalisations are on the rise,

and this is during summer weather ... and with reinfections occuring

 

On the plus side, Moderna variant vaccine(s) are looking promising, including against the K4/5 variants.

[tobyjugg2]

Covid

 

The new BA.4 and BA.5 Covid variants are beginning to bite, as covid infections jumped 43 per cent after the jubilee weekend. Meanwhile hospitalisations jumped by 43 per cent in a week on Tuesday.

 

Monkeypox

 

National concern over monkeypox continues to grow as 793 cases have been recorded and the UK Health Security Agency have decided to pre-emptively offer vaccines to gay, bisexual and men who have sex with men, who are seen to be at higher risk.

 

Polio

 

A national incident has been declared after poliovirus was detected in wastewater in London.

 

The virus, which can cause paralysis in rare cases, was identified in sewage samples taken from the capital between February and May 2022, according to the UK Health Security Agency.

 

UKHSA said it was “likely” there has been spread of a vaccine-derived poliovirus type 2 (VDPV2) between closely linked people in North-East London, with infected individuals believed to be shedding the virus in their faeces. So far, no suspected cases have been reported or confirmed.

 

- Independent health news letter