fortunately: “lots of choices”
It hasn’t become resistant to penicillin despite 70+ years of penicillin usage.
My understanding is that it can sometimes have resistance to some of the tablet alternatives used for people who are penicillin allergic, though there are ‘drip’ antibiotics for severe Group A Strep infections where resistance isn’t seen (& that includes non-penicillin based ‘drip’ alternatives, too), so there are reliable options for severe Group A Strep disease even for those allergic to penicillin.